First Minister Eluned Morgan urged people to take the weather warnings seriously.
“Red means there is a potential danger to life,” she said.
Ms Morgan advised people to only travel if it was “necessary”.
Meanwhile, Deputy First Minister Huw Irranca-Davies warned there may be very significant impacts from Storm Darragh and urged people to take extreme care over the weekend.
He added the government would be monitoring the situation closely.
People have been warned to stay alert for flying debris and falling trees, along with large waves hitting sea fronts, homes and roads.
Power cuts and travel disruption are also possible, the Met Office added, with the M48 Severn Bridge closed in both directions.
The RNLI advised those living near or visiting the Welsh coast to exercise “extreme caution” and Cardiff Airport has said it will be closed from 03:00 to 11:00.
Transport for Wales said train services may be subject to “short notice delays, alterations, and cancellations” and advised people to check their journeys before travelling.
Sharon Scott, of Betsi Cadwaladr health board, said people should “take extra care”, adding: “When severe weather is expected we always put plans in place to ensure the safety of our patients and staff and to ensure our services are protected in the event of disruption as far as possible.”
A balaclava-clad football hooligan who hurled a deadly pyrotechnic flare at opposing European fans was unmasked as a serving British police officer.Detective Co
Venus and Jupiter will be the easiest to spot due to their brightness, while Mars will have a distinct reddish hue. "Uranus is technically visible with the nake
A teenager's plan to carry out a school shooting after killing three members of his family was "extremely shocking, distressing and upsetting", a council leader
Christine Charlesworth, who designed the statue of Behn, said: "My Aphra is walking but glancing behind her because she is carrying interesting things such as a