PSV v Liverpool (20:00 GMT)
With Liverpool already guaranteed first or second spot in the Champions League table, manager Arne Slot has left a whole host of first-team regulars out of the 21-man squad for the trip to PSV Eindhoven.
Captain Virgil van Dijk, Trent Alexander-Arnold and Mohamed Salah have all been left behind while Alisson Becker, Ibrahima Konate, Ryan Gravenberch, Alexis Mac Allister, Dominik Szoboszlai and Luis Diaz will also not make the trip.
Curtis Jones and Diogo Jota are absent through injury.
Liverpool squad v PSV: Caoimhin Kelleher, Vitezslav Jaros, Harvey Davies, Conor Bradley, Isaac Mabaya, Jarell Quansah, Amara Nallo, Andy Robertson, Kostas Tsimikas, James Norris, Wataru Endo, James McConnell, Tyler Morton, Trey Nyoni, Harvey Elliott, Kieran Morrison, Darwin Nunez, Federico Chiesa, Cody Gakpo, Jayden Danns, Trent Kone-Doherty.
Defeat at the qualifying stages of the Champions League in August had limited Clement's summer transfer budget amid a worsening financial picture off the pitch.
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