The No. 14 Kentucky Wildcats will try to get back on track as they face the struggling South Carolina Gamecocks on Saturday. Kentucky is 15-7 (4-5 SEC) in its first season under head coach Mark Pope, but the Wildcats have lost four of their last five. South Carolina (10-12), meanwhile, is last in the SEC at 0-9 in conference play. South Carolina lists Myles Stute as out, while Kentucky has ruled out Kerr Kriisa. Lamont Butler and Jaxson Robinson are both questionable for the Wildcats. 

Tipoff from Rupp Arena in Lexington, Ky., is set for noon ET. The Wildcats are 11.5-point favorites in the latest South Carolina vs. Kentucky odds from SportsLine consensus, while the over/under for total points scored is 151.5. Before making any Kentucky vs. South Carolina picks, check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 14 of the 2024-25 season on a 208-149 betting roll (+2275) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has set its sights on Kentucky vs. South Carolina. You can head to SportsLine to see its picks. Here are several college basketball betting lines and trends for South Carolina vs. Kentucky: 

• Kentucky vs. South Carolina spread: Kentucky -11.5
• Kentucky vs. South Carolina over/under: 151.5 points
• Kentucky vs. South Carolina money line: Kentucky -699, SC +497
• Kentucky vs. South Carolina picks: See picks at SportsLine
• Kentucky vs. South Carolina streaming: FuboTV (Try for free)

Why you should back Kentucky

The Wildcats have struggled in the heart of SEC play, but this is a great opportunity to bounce back against a potentially overmatched foe. South Carolina is not only winless in the SEC, the Gamecocks have lost three of their last four conference road games by double digits. They are just 3-5 against the spread on the road this season.

Kentucky has demonstrated a high ceiling this season, beating teams such as Duke, Gonzaga, Florida and Tennessee. Guard Otega Oweh leads the team with 16 points per game, and getting Butler back in the lineup would give the Wildcats another strong secondary scorer and a top defender. See which team to pick here.

Why you should back South Carolina

Despite the poor overall campaign, South Carolina has still covered in three of its last four games overall. The Gamecocks are .500 against the spread on the season, so the market has fairly valued them. Kentucky is in its worst stretch of the season, losing back-to-back games by double digits. 

Forward Colin Murray-Boyles is a high-level player who averages 15.5 points and 8.8 rebounds per game. Guard Jamariu Thomas is the top perimeter threat, scoring 13.3 points per game on 37.2% shooting from 3-point territory. See which team to pick here.

How to make South Carolina vs. Kentucky picks

SportsLine’s model is going Over on the total, projecting 153 combined points. It also says one side of the spread hits well over 60% of the time. You can only get the pick at SportsLine.

So who wins Kentucky vs. South Carolina and which side of the spread hits well over 60% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up more than $2,200 on its college basketball picks dating back to 2023, and find out.