The bus is about the size of an ambulance, and is equipped with reclining couches, dressing trolleys, and is staffed by specialist burns nurses and therapists.
The mobile clinic will travel to large Tesco supermarket car parks, on pre-arranged days, where patients can book appointments.
Tara Hanmer, senior sister for burns outpatients and outreach, said: “I’m so immensely proud of my team, who have embraced the concept, which includes driving around a 3,000kg, 7.5m (25ft) bus.”
The project will be piloted for one year following donations from the London and South East Burns Network and the Doris Macer Foundation.
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